Helps you reach and maintain a healthy weight.
Alli, XenicalThere may be other brand names for this medicine.
When This Medicine Should Not Be Used
Do not use this medicine if you have had an allergic reaction to orlistat, if you have gallbladder disease, or if you have a disorder that keeps you from absorbing or digesting food. Do not use this medicine if you are pregnant.
How to Use This Medicine
- Take your medicine as directed.
- Take this medicine during each main meal or up to 1 hour after a meal.
- Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
If a dose is missed:
- If you miss a meal or eat a fat-free meal, you can skip your dose of the medicine.
- If you forget to take the medicine with a meal, you may take it up to 1 hour after the meal. If more than 1 hour has passed, do not take the medicine. Wait until it is time for your next dose to take the medicine. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you take cyclosporine (Gengraf®, Neoral®, Sandimmune®). Cyclosporine must be used at least 3 hours before or 3 hours after you use orlistat.
- If you use multivitamins, take them at least 2 hours before or 2 hours after you take orlistat.
- Tell your doctor if you also use levothyroxine (Levothroid®, Levoxyl®, Synthroid®). Levothyroxine must be used at least 4 hours before or 4 hours after you take this medicine.
- Your doctor should know if you are also using medicine to treat diabetes (such as insulin, glyburide, glipizide, metformin, Glucophage®, or Glucotrol®), a blood thinner (such as warfarin, Coumadin®), or any other medicines to help you lose weight.
Warnings While Using This Medicine
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Make sure your doctor knows if you are breastfeeding, or if you have kidney problems (such as kidney stones), liver disease, underactive thyroid, or an eating disorder (such as anorexia or bulimia).
- Make sure your doctor knows if you have diabetes. He may change your diabetes medicine if you lose weight.
- Bowel side effects can be worse if you eat a meal that is more than 30% fat. This medicine prevents you from absorbing some of the fat from food. The undigested fat comes out in your bowel movements. To reduce side effects, divide your daily intake of fat evenly over your 3 main meals each day.
- Carefully follow your doctor's instructions for a well-balanced, reduced-calorie meal plan.
- Take a multivitamin supplement that contains vitamins D, E, and K, and beta-carotene. You may need this because orlistat keeps you from absorbing some of the vitamins from food.
- Stop using this medicine and check with your doctor right away if you have pain or tenderness in the upper stomach, unusual itching, yellowing of the eyes or skin, dark urine, loss of appetite, or pale stools. These may be signs of a serious liver problem.
- Weight loss with this medicine may increase your risk for gallstones. Check with your doctor right away if you have severe stomach pain with nausea and vomiting.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.Blood and urine tests may be needed to check for unwanted effects.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Change in how much or how often you urinate, or painful urination
- Dark-colored urine or pale stools
- Nausea, vomiting, loss of appetite, or pain in your upper stomach
- Red or dark brown urine
- Severe diarrhea
- Severe stomach pain with nausea and vomiting
- Sharp back pain just below the ribs
- Swelling of your legs and feet
- Yellowing of your skin or the whites of your eyes
If you notice these less serious side effects, talk with your doctor:
- Fever, chills, cough, runny or stuffy nose, sore throat, and body aches
- Increases in bowel movements, loss of bowel control, or the need to have a bowel movement right away
- Passing gas with oily discharge
- Passing oil or fat with your bowel movements or between bowel movements