Treats certain kinds of leukemia (blood cancer).
MyleranThere may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not use this medicine if you have had an allergic reaction to busulfan, or if you are pregnant.
How to Use This Medicine
- Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
- Take your medicine as directed.
- Swallow the tablet whole. Do not crush, break, or chew it. Drink plenty of fluids while using this medicine.
If a dose is missed:
- This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor for instructions.
How to Store and Dispose of This Medicine
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also using itraconazole (Sporanox®), thioguanine (Tabloid®), or other cancer medicines. Tell your doctor about all chemotherapy or radiation treatments you have had.
Warnings While Using This Medicine
- This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Make sure your doctor knows if you are breast feeding. Tell your doctor if you have thalassemia, myasthenia gravis, or a history of seizures or head injury.
- This medicine may cause a rare but serious lung problem, which may develop months or years after you stop using the medicine. Signs of this problem include cough, trouble breathing, and low fever. These symptoms may come on suddenly or develop slowly. Talk with your doctor about this possible risk.
- Using this medicine may increase your risk of developing other kinds of cancer, or having a recurrence of leukemia. Talk with your doctor about this risk.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Bloody or black, tarry stools.
- Fever, chills, cough, runny or stuffy nose, sore throat, and body aches.
- Chest pain or pressure, trouble breathing.
- Coughing up blood.
- Loss of appetite, nausea, vomiting, weight loss, darkening of your skin.
- Unusual bleeding, bruising, or weakness, pale skin.
If you notice these less serious side effects, talk with your doctor:
- Change in your menstrual periods.
- Dry mouth, nose, or eyes, decreased sweating.
- Hair loss.
- Problems with vision.
- Skin rash.
- Swelling of your breasts.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088