Treats muscle stiffness in the arms and muscle spasms in the neck, eyelids, and around the eyes. Treats excessive underarm sweating. Prevents chronic migraine headaches. Treats overactive bladder and loss of bladder control. Also used to improve the appearance of facial lines or wrinkles. This is a botulinum toxin A product.
Botox, Botox CosmeticThere may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not receive this medicine if you have had an allergic reaction to any botulinum toxin product or onabotulinumtoxinA. You should not receive this medicine if you have a skin infection where the shot will be given. You should not receive this medicine if you are not able to urinate or have a urinary tract infection.
How to Use This Medicine
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given by a healthcare provider as a shot under your skin or into a muscle.
- You may be given medicine to numb the area where the shot will be injected. If you receive the medicine around your eyes, you may be given eye drops or ointment to numb the area. After your injection, you may need to wear a protective contact lens or eye patch.
- If you are being treated for excessive sweating, shave your underarms but do not use deodorant for 24 hours before your injection. Avoid exercise, hot foods or liquids, or anything else that could make you sweat for 30 minutes before your injection.
- The recommended re-treatment schedule for chronic migraine is every 12 weeks.
- This medicine works slowly. Once your condition has improved, the medicine will last about 3 months, then the effects of the medicine will slowly go away. You might need more injections to treat your condition after the medicine wears off.
- Muscle spasms in the eyelids should improve within 3 to 10 days after your injection.
- Eye muscle problems should improve 1 or 2 days after the injection, and the improvement should last for 2 to 6 weeks.
- Neck pain should improve within 2 to 6 weeks after your injection.
- Arm stiffness should improve within 4 to 6 weeks after your injection.
- Facial lines or wrinkles should improve 1 or 2 days after your injection.
- This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
If a dose is missed:
- Call your doctor or pharmacist for instructions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you also using aspirin, a muscle relaxer, medicine for an infection (such as amikacin, gentamicin, streptomycin, tobramycin, garamycin, TOBI®), or a blood thinner (such as ticlopidine, warfarin, Coumadin®, Jantoven®, Ticlid®).
- Tell your doctor if you have received an injection of any botulinum toxin product within the past 4 months.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding. Tell your doctor if you have breathing problems (such as asthma, bronchitis, or emphysema), bladder problems, bleeding problems, diabetes, multiple sclerosis, or a droopy eyelid. Tell your doctor if you have nerve or muscle problems, ALS (Lou Gehrig disease), Lambert-Eaton syndrome, or myasthenia gravis. Tell your doctor if you have trouble speaking or swallowing, or have ever had face surgery.
- Serious muscle reactions have been reported within hours to weeks after receiving this medicine. If you have muscle weakness, loss of bladder control, or trouble swallowing, talking, or breathing, call your doctor right away. These problems could be life-threatening and may require immediate treatment in a hospital or clinic.
- This medicine may make your muscles weak or cause vision problems. Do not drive, use machines, or do anything else that could be dangerous if you feel weak or are not able to see well.
- There are some warnings that only apply if are receiving this medicine to treat the following:
- Muscle spasms in the eyelids: This medicine may reduce blinking, which can raise the risk of eye problems such as corneal exposure and ulcers. Tell your doctor right away if you notice that you are blinking less than usual or your eyes feel dry.
- Urinary incontinence: This medicine may cause autonomic dysreflexia, which can be a life-threatening condition. Call your doctor right away if you have a headache, increased sweating, slow heartbeat, warmth or redness in your face, neck, or arm, or have problems urinating.
- Overactive bladder: Check with your doctor right away if you have difficulty urinating or a burning sensation while urinating.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Change in how much or how often you urinate, painful urination
- Chest pain, uneven heartbeat
- Eye pain, redness in the whites of your eyes
- Loss of bladder control
- Trouble swallowing, breathing, or speaking
- Unusual weakness in other muscles (not where the shot was given)
If you notice these less serious side effects, talk with your doctor:
- Blurred or double vision
- Droopy eyelid, dry eyes
- Fever, chills, cough, stuffy or runny nose, sore throat, and body aches
- Pain in your neck, back, arms, or legs
- Redness, pain, tenderness, bruising, swelling, or weakness where the shot was given
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088