Paclitaxel Protein-Bound (pak-li-TAX-el PROE-teen - bownd)
Treats breast cancer and lung cancer.
AbraxaneThere may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not receive this medicine if you have had an allergic reaction to paclitaxel protein-bound injection. You should not receive this medicine if you are pregnant, or if you have a low number of white blood cells.
How to Use This Medicine
- Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
- You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
- Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
If a dose is missed:
- This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also using cimetidine (Tagamet®), fluoxetine (Prozac®), gemfibrozil (Lopid®), rifampicin (Rifadin®, Rimactane®), verapamil (Calan®), medicine to treat an infection (such as erythromycin, itraconazole, ketoconazole, voriconazole, Nizoral®), medicine to treat HIV infection (such as efavirenz, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir, Atripla®, Norvir®), or medicine to treat seizures (such as carbamazepine, phenytoin, Dilantin®, Tegretol®).
Warnings While Using This Medicine
- This medicine can cause problems, such as birth defects, if it is used by the mother while she is pregnant or by the father when his sexual partner becomes pregnant. Tell your doctor right away if a pregnancy occurs during your treatment.
- Make sure your doctor knows if you are breastfeeding, or if you have liver disease, kidney disease, or neuropathy or other nerve problems.
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Avoid people who are ill, and wash your hands often. Brush and floss your teeth gently, do not play rough sports, and be careful with sharp objects.
- This medicine is made from donated human blood. Some human blood products have transmitted viruses to people who have received them. Human donors and donated blood are both tested for viruses before the medicine is prepared. Although the risk of getting a virus is low, talk with your doctor if you are concerned.
- Check with your doctor right away if you have burning, numbness, tingling, or painful sensations in the arms, hands, legs, or feet. These could be symptoms of sensory neuropathy.
- Cancer medicines can cause nausea and/or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Fever, chills, cough, sore throat, or body aches
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet
- Ongoing vomiting or diarrhea, extreme thirst
- Slow, fast, or uneven heartbeat
- Trouble breathing, lightheadedness
- Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
- Diarrhea, vomiting
- Hair loss
- Joint or muscle pain
- Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
- Weakness, tiredness
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088