Treats rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. This medicine is a tumor necrosis factor (TNF) blocker.
Simponi, Simponi AriaThere may be other brand names for this medicine.
When This Medicine Should Not Be Used
You should not receive this medicine if you have had an allergic reaction to golimumab.
How to Use This Medicine
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.Simponi® Aria? must be injected slowly, so the IV will need to stay in place for 30 minutes.
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.
- A nurse or other health provider will give you this medicine.
- You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
- Use a new needle and syringe each time you inject your medicine.
- You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
- Check the liquid in the syringe or autoinjector. It should be clear and colorless or slightly yellow. Do not use Simponi® if it is cloudy, discolored, or has large particles in it. Do not shake the medicine.
- This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine
- If you store this medicine at home, keep it in the refrigerator. Do not freeze.Protect the medicine from direct light. Keep the medicine in the original package until you are ready to use it.
- Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. You will also need to throw away old medicine after the expiration date has passed.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Tell your doctor if you use abatacept (Orencia®), adalimumab (Humira®), anakinra (Kineret®), certolizumab (Cimzia®), etanercept (Enbrel®), infliximab (Remicade®), rituximab (Rituxan®), or tocilizumab (Actemra®).
- Make sure your doctor knows if you use medicine that weakens your immune system, such as azathioprine (Imuran®), methotrexate (Rheumatrex®, Trexall®) cancer medicines, or steroids (such as dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone, Medrol®). Make sure your doctor knows if you also use cyclosporine (Gengraf®, Neoral®, Sandimmune®), theophylline (Theo-Dur®), or a blood thinner (such as warfarin, Coumadin®, Jantoven®).
- This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.
Warnings While Using This Medicine
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have cancer, congestive heart failure, diabetes, chronic obstructive pulmonary disease (COPD), psoriasis, immune system problems, Wegener granulomatosis, or a condition that affects your nervous system (such as multiple sclerosis or a history of Guillain-Barré syndrome). Tell your doctor if you have an infection, a history of hepatitis B, tuberculosis (TB) or a history of TB, or have been in close contact with someone who has active TB. Tell your doctor if you are allergic to latex.
- You will need to have a skin test for tuberculosis before you start using this medicine. Tell your doctor if you or anyone in your home has ever had a positive reaction to a tuberculosis skin test.
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Avoid people who are ill, and wash your hands often. Brush and floss your teeth gently, do not play rough sports, and be careful with sharp objects.
- You may get infections more easily while you use this medicine. Call your doctor right away if you have any symptoms of an infection, such as fever, chills, or a cough that does not go away.
- Check with your doctor right away if you have chest pain, trouble breathing, or swelling of the hands, feet, or lower legs. These may be symptoms of congestive heart failure.
- This medicine may increase your risk of certain types of cancer, such as leukemia or lymphoma. Talk with your doctor if you have unusual bleeding, bruising, or weakness, swollen lymph glands in the neck, underarms, or groin, or unexplained weight loss.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash
- Bone pain
- Changes in vision
- Dark urine or pale stools, nausea, vomiting, loss of appetite, pain in your upper stomach, yellow skin or eyes
- Fever, chills, cough, sore throat, and body aches
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet
- Rapid weight gain, swelling in your hands, ankles, or feet
- Sores or white patches on your lips or mouth
- Swollen lymph glands in the neck, underarms, or groin
- Trouble breathing, chest pain, cold sweats, and bluish-colored skin
- Unexplained weight loss
- Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
- Mild skin rash
- Redness, itching, pain, or swelling where the needle was placed or the shot was given
- Stuffy or runny nose