Cefpodoxime 

(sef pode ox' eem)

WHY is this medicine prescribed?

Cefpodoxime is used to treat certain infections caused by bacteria such as bronchitis (infection of the airway tubes leading to the lungs); pneumonia; gonorrhea (a sexually transmitted disease); and infections of the skin, ear, sinuses, throat, tonsils, and urinary tract. Cefpodoxime is in a class of medications called cephalosporin antibiotics. It works by stopping the growth of bacteria.

Antibiotics such as cefpodoxime will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

HOW should this medicine be used?

Cefpodoxime comes as a tablet and suspension (liquid) to take by mouth. It is usually taken every 12 hours for 5 to 14 days depending on the condition being treated. A single dose is given to treat gonorrhea. Take the tablet with food; the suspension can be taken with or without food. Take cefpodoxime at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cefpodoxime exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the suspension well before each use to mix the medication evenly.

You should begin to feel better during the first few days of treatment with cefpodoxime. If your symptoms do not improve or get worse, call your doctor.

Continue to take cefpodoxime until you finish the prescription even if you feel better. If you stop taking cefpodoxime too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics..

Are there OTHER USES for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What SPECIAL PRECAUTIONS should I follow?

Before taking cefpodoxime,

  • tell your doctor and pharmacist if you are allergic to cefpodoxime; any other cephalosporin antibiotic such as cefaclor, cefadroxil,cefazolin (Ancef, Kefzol), cefdinir, cefditoren (Spectracef), cefepime (Maxipime), cefixime (Suprax), cefotaxime (Claforan), cefotetan, cefoxitin (Mefoxin), cefprozil, ceftaroline (Teflaro), ceftazidime (Fortaz, Tazicef, in Avycaz), ceftibuten (Cedax), ceftriaxone (Rocephin), cefuroxime (Zinacef) and cephalexin (Keflex);penicillin antibiotics; or any other medications. Also tell your doctor if you are allergic to any of the ingredients in cefpodoxime tablets or suspension.Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antacids (Maalox, Mylanta, others), cimetidine, colistimethate (Coly-Mycin M), diuretics ('water pills'), famotidine (Pepcid), gentamicin, kanamycin, neomycin (Neo-Fradin), nizatidine (Axid), polymixin B, probenecid (Probalan), ranitidine (Zantac), streptomycin, tobramycin. and vancomycin (Vancocin). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had gastrointestinal disease (GI; affecting the stomach or intestines), especially colitis (condition that causes swelling in the lining of the colon [large intestine]), or kidney disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking cefpodoxime, call your doctor.
  • if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that cefpodoxime suspension is sweetened with aspartame that forms phenylalanine.

What SPECIAL DIETARY instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do IF I FORGET to take a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What SIDE EFFECTS can this medicine cause?

Cefpodoxime may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• nausea

  • vomiting
  • diarrhea
  • stomach pain
  • swelling, redness, irritation, burning, or itching of the vagina
  • white vaginal discharge
  • headache

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:

  • watery or bloody stools, stomach cramps, or fever during treatment or for up to two or more months after stopping treatment

• rash

• itching

• hives

  • difficulty breathing or swallowing
  • wheezing
  • a return of fever, sore throat, chills, or other signs of infection

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from light and excess heat and moisture (not in the bathroom). Keep liquid medicine in the refrigerator, tightly closed, and dispose of any unused medication after 14 days.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

What should I do in case of OVERDOSE?

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include the following:

• nausea

  • vomiting
  • diarrhea
  • stomach pain

What OTHER INFORMATION should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to cefpodoxime.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking cefpodoxime.

If you are diabetic and test your urine for sugar, use Clinistix or TesTape (not Clinitest) to test your urine while taking this drug.

Do not let anyone else take your medication. Your prescription is probably not refillable. .

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand Names
  • Banan®[¶]
  • Vantin®[¶]
  • Also available generically

This branded product is no longer on the market. Generic alternatives may be available.

Please note, not all procedures included in this resource library are available at Henry Ford Allegiance Health or performed by Henry Ford Allegiance Health physicians.

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This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.

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