Lobular Carcinoma in Situ
Lobules are a normal part of the breast which produces milk. Lobular carcinoma in situ (LCIS) occurs when abnormal cells grow in these lobules of the breast. These abnormal cells do not grow in an uncontrolled manner or spread to other areas of the body like cancer. However, LCIS is considered a risk factor for future breast cancer .
It is not clear exactly what causes LCIS. It is probably a combination of genetics and environment.
LCIS is more common in premenopausal women, generally between 40-50 years old. Other factors that may increase your chance of LCIS include:
- Family members with breast cancer
- Increased exposure to estrogen
- Use of hormone replacement therapy
LCIS does not have symptoms.
LCIS does not appear on imaging tests, nor can it be felt during a manual breast exam. It is generally found by accident during biopsy of other nearby breast tissue.
LCIS does not require treatment.
Frequent follow-up visits and tests to monitor any changes in the breast tissue may be recommended because of the increased risk of breast cancer. If you detect any changes in either breast, call your doctor right away for an appointment.
Other breast cancer prevention treatments may be recommended based on your overall risk of developing breast cancer. If you have a high risk of developing future breast cancer, your doctor may recommend:
- Medications—To block estrogen receptors on breast tissue cells.
- Surgery—A double mastectomy with reconstruction may be an option under special circumstances. It is generally considered to be an aggressive option.
Talk to your doctor about the risks and benefits of having these treatments.
There are no current guidelines to prevent LCIS because it is not known what causes it.
- Michael Woods, MD
- Reviewed: 12/2014
- Updated: 12/20/2014
Please note, not all procedures included in this resource library are available at Henry Ford Allegiance Health or performed by Henry Ford Allegiance Health physicians.
All EBSCO Publishing proprietary, consumer health and medical information found on this site is accredited by URAC. URAC's Health Web Site Accreditation Program requires compliance with 53 rigorous standards of quality and accountability, verified by independent audits. To send comments or feedback to our Editorial Team regarding the content please email us at HLEditorialTeam@ebscohost.com.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.